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Neoral

Generic Neoral (Cyclosporine)

Cyclosporine is used to prevent organ rejection after a kidney, liver, or heart transplant.
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Long time: Neoral

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Visual appearance yellow-white oblong soft Nworal capsules imprinted in Neorak with "NVR 50mg". Renal dysfunction, hypertension, headache, GI disturbances, hirsutism, hypertrichosis, leg cramps, pain, tremor, paresthesia, edema, dizziness, gum hyperplasia, liver Neodal increased risk of infections or malignancies, progressive multifocal leukoencephalopathy, hyperkalemia, thrombotic microangiopathy, possible encephalopathy. A side Neorsl is an unwanted response to Neoral medication when it is taken in normal doses. Talk to your doctor if you have any concerns. May increase your risk of getting an infection. Peter, D. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. Stop taking the medication and seek immediate medical attention if any of the following occur:. Neoral Drug Class Back to Top. It has also been found helpful in the treatment of a kidney condition known as nephrotic syndrome. Side Effects of Neoral Back to Top. Drug Information available for: Cyclosporine. The results of trough CyA determinations did not become known to investigators during the study. Dose adjustments should be made in transplant patients to minimize possible organ rejection due to low concentrations. Your blood pressure will also be measured regularly. Your Neorl will adjust your dose to one that is ideal for you. Active Comparator: 2 taking Neoral. Ask your doctor or pharmacist if you are unsure about how much medicine to take or when to take it. Your doctor should monitor your blood pressure regularly while you are taking this medication. You should seek medical advice in relation to medicines and use only as directed by a healthcare professional. Neoral Cautionary Labels Back to Top. This Neoral is increased when you also use certain other medicines, including: antivirals, cholesterol-lowering drugs, chemotherapyinjected antibioticsmedicine for bowel disorders, medicines to treat autoimmune disordersmedicine to prevent organ transplant rejection, stomach acid reducers TagametZantacand some pain or arthritis medicines including aspirinTylenolAdviland Aleve. No well-controlled studies have been done in humans. If your doctor decides to stop your treatment, return any leftover medicine to the pharmacist. Nicholls, H. Additional safety, efficacy and tolerability evaluations were made at the end of weeks 28, 36, 44 and Your comment will be reviewed and published at the journal's discretion. For the active ingredient ciclosporin. I agree Neooral the terms and conditions. Nicholls, H. Add comment Cancel. What is the medicines and poisons schedule? The maximum permitted dose for each formulation was 5. Visual appearance yellow-white oblong soft gelatin capsule, imprinted in red with "NVR 10". Additional safety, efficacy and tolerability evaluations were made at the end of weeks Nelral, 36, 44 and By the week 52 visit, there was a total of 79 dose reductions in 50 patients due to elevated serum creatinine in the Neoral group and 60 dose reductions in 42 patients for the same reason in the SIM group. Written informed consent was a prerequisite for the inclusion of all patients. Skip to Content. This is normal and does not mean that the medication is damaged or unsafe to use. Combe, M. How was your experience with Neoral? In patients with severe psoriasis in whom conventional therapy is ineffective or inappropriate and the disease has caused a significant interference with the quality of life. Dose adjustments should be made Neoral transplant patients to minimize possible organ rejection due to low concentrations. This dose is usually continued for 3 to 6 months and then decreased gradually until it is stopped, about one year after the transplant. Hein, K. Follow these instructions carefully. Ask your pharmacist if you have any questions about the new kind of cyclosporine you receive at the pharmacy. Grapefruit and grapefruit juice may interact with Neoral and lead to potentially dangerous effects. Subject alert. A side Neorl is an Neogal response to a medication when it is taken in normal eNoral. Hold the syringe over the liquid in your glass and press down on the Neoral to place the medication in the glass. The two treatment groups were similar with respect to demographic characteristics, disease characteristics and use of concomitant medications at study entry safety population. Many drugs can interact with Neoral. Consumer Contact:. People with reduced kidney function should not receive more than 2. Last Update Posted : June 22, Comparison of blood concentrations in the published literature with blood concentrations obtained using current assays must be done with detailed knowledge of the assay methods employed. This is because the immune system treats the new organ as an invader. Feutren G. Email Address. You have entered an invalid code. Lopes Vaz. Mur, H. In animal studies, pregnant animals were given this medication and had some babies born with problems. Neoral reviews.
Common use

Cyclosporine lowers your body's immune system. The immune system helps your body fight infections. The immune system can also fight or "reject" a transplanted organ such as a liver or kidney. This is because the immune system treats the new organ as an invader.

Cyclosporine is used to prevent organ rejection after a kidney, liver, or heart transplant.

Dosage and direction

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended.

You may take cyclosporine with or without food, but take it the same way each time. Cyclosporine should be given in two separate doses each day. Try to take the medication at the same dosing times each day. Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon.



Precautions

Avoid exposure to sunlight, sunlamps, or tanning beds. Cyclosporine can make your skin more sensitive to sunlight, and a sunburn may result. Wear protective clothing and use sunscreen (SPF 15 or higher) when you are outdoors.

If you are being treated for psoriasis, you should not receive light therapy (PUVA or UVB) or radiation treatments while you are receiving cyclosporine. Make sure all doctors involved in your care know you are taking cyclosporine.



Contraindications

You should not use this medication if you are allergic to cyclosporine. You may not be able to use cyclosporine if you have:

kidney disease;

untreated or uncontrolled high blood pressure; or

any type of cancer.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take cyclosporine:

psoriasis that has been treated with PUVA, UVB, radiation, methotrexate (Trexall), or coal tar; or

if you are also taking an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), and others.

It is not known whether cyclosporine is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. Cyclosporine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.



Possible side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

urinating less than usual or not at all;

drowsiness, confusion, mood changes, increased thirst;

swelling, weight gain, feeling short of breath;

blurred vision, headache or pain behind your eyes, sometimes with vomiting;

seizure (convulsions);

muscle pain or weakness, fast heart rate, feeling light-headed;

signs of infection such as fever, chills, sore throat, flu symptoms;

pale skin, easy bruising or bleeding, unusual weakness; or

nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

tremors or shaking;

increased hair growth;

headache or body pain;

diarrhea, constipation, vomiting; or

numbness or tingly feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.



Drug interaction

Many drugs can interact with cyclosporine. Below is just a partial list. Tell your doctor about all other medications you are using, especially: etoposide (VePesid, Etopophos); lithium (Eskalith, Lithobid); methotrexate (Rheumatrex, Trexall); nefazodone; repaglinide (Prandin); St. John's wort;

an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik);

a heart or blood pressure medication such as candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro, Avalide), losartan (Cozaar, Hyzaar), valsartan (Diovan), telmisartan (Micardis), or olmesartan (Benicar);

medicines used to treat ulcerative colitis, such as mesalamine (Pentasa) or sulfasalazine (Azulfidine);

other medicines used to prevent organ transplant rejection, such as sirolimus (Rapamune) or tacrolimus (Prograf);

pain or arthritis medicines such as aspirin (Anacin, Excedrin), acetaminophen (Tylenol), diclofenac (Voltaren), etodolac (Lodine), ibuprofen (Advil, Motrin), indomethacin (Indocin), naproxen (Aleve, Naprosyn), and others;

IV antibiotics such as amphotericin B (Fungizone, AmBisome, Amphotec, Abelcet), amikacin (Amikin), bacitracin (Baci-IM), capreomycin (Capastat), gentamicin (Garamycin), kanamycin (Kantrex), streptomycin, or vancomycin (Vancocin, Vancoled);

antiviral medicines such as adefovir (Hepsera), cidofovir (Vistide), or foscarnet (Foscavir); or

cancer medicine such as aldesleukin (Proleukin), carmustine (BiCNU, Gliadel), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), streptozocin (Zanosar), or tretinoin (Vesanoid).



Missed dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.



Overdose

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose can cause nausea, vomiting, pain in your upper stomach, loss of appetite, jaundice (yellowing of the skin or eyes), and urinating less than usual or not at all.

Storage

Store cyclosporine at room temperature away from moisture and heat.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. The specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Antidepressants

Antidepressants are psychotropic substances that are used in depression treatment.
The drug works by:

  • Increasing disposition
  • Decreasing fatigue, apathy, anxiety
  • Relief of emotional tension
  • Improves mental activity
  • Normalization sleep and appetite

In a healthy human being which is not affected by depression antidepressants do not exert any positive effects. Although the above positive effects manifest all the antidepressants do have specific side-effects that may impair your daily life. For example a feeling of tiredness is a common side-effect in the beginning of the antidepressant therapy which passes within a few weeks. It is important to take the medicine even after you start feeling better. A consultation with you health care provider is necessary before stopping the treatment as for many antidepressants the treatment should be stopped gradually.

Different group of antidepressants currently exist among them are:

  • MAO inhibitors - monoamine oxidase inhibitors
    • Selective MAO inhibitors
    • Non-selective MAO inhibitors
  • Preparations that block neuronal reuptake of amines
    • Non-selective blockers of norepinephrine and serotonin reuptake
    • Selective serotonin reuptake inhibitors
    • Selective norepinephrine reuptake inhibitors
  • Monoamine receptors agonists